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Dr. Gaila Mackenzie-Strawn

CFMP, DNM, MS, DC ,CTN

5-HTP Reduces Symptoms of Anxiety Disorder

On : 19 March, 2013

In : Anxiety

1 Comments

Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.

Kahn RS, Westenberg HG, Verhoeven WM, Gispen-de Wied CC, Kamerbeek WD.

Source

Department of Biological Psychiatry, University Hospital, Utrecht, The Netherlands.

Abstract

A double-blind placebo-controlled study of 5-HTP and clomipramine was carried out on 45 patients suffering from anxiety disorders (DSM-III). Clomipramine has shown to be effective in that it induced significant improvement on all rating scales as compared to placebo. 5-HTP showed a moderate reduction of the symptomatology on the 90-item symptoms checklist (SCL-90) and the State Scale of the Spielberger State-Trait Anxiety Inventory. Clomipramine and 5-HTP differed in their efficacy in that 5-HTP did not affect the associated depressive symptomatology. 5-HTP Reduces Symptoms of Anxiety Disorder

Int Clin Psychopharmacol. 1987 Jan;2(1):33-45.

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