A double- blind study was conducted comparing the effects of ginger and ibuprofen on pain in women with menstrual cramps.

Participants were 150 students (18 years old and over) with menstrual cramps from the dormitories of two medical universities who were alternately divided into three equal groups.

Students in the ginger group took 250 mg capsules of ginger rhizome powder four times a day for three days from the start of their menstrual period.

Members of the other groups received 250 mg of ibuprofen.

Menstrual cramps (dysmenorrhea) decreased in both groups and no differences were found between the groups in severity of dysmenorrhea, pain relief, or satisfaction with the treatment.

Ginger was as effective as ibuprofen in relieving pain in women with menstrual cramps.

J Altern Complement Med. 2009.

Comparison of effects of ginger and ibuprofen on pain in women with primary dysmenorrhea.

This was a double-blind comparative clinical trial.

Participants were 150 students (18 years old and over) with primary dysmenorrhea from the dormitories of two medical universities who were alternately divided into three equal groups.

Students in the ginger group took 250 mg capsules of ginger rhizome powder four times a day for three days from the start of their menstrual period.

Members of the other groups received 250 mg of ibuprofen.

Dysmenorrhea decreased in both groups and no differences were found between the groups in severity of dysmenorrhea, pain relief, or satisfaction with the treatment.

Ginger was as effective as ibuprofen in relieving pain in women with primary dysmenorrhea.

Magnesium–a new therapeutic alternative in primary dysmenorrhea.

Menstrual pain correlated with fat intake
AARHUS, DENMARK. Menstrual pain (menstrual cramps, dysmenorrhea) is believed to be associated with an elevated level of PG2 prostaglandins. PG2 prostaglandins are synthesized from the omega-6 fatty acid, arachidonic acid and are known to be pro-inflammatory. The formation of PG2 prostaglandins competes with the formation of PG3 prostaglandins from the omega-3 fatty acid, eicosapentaenoic acid (EPA), the main component of fish oil. PG3 prostaglandins are anti-inflammatory.

Danish researchers have completed a study to determine if the ratio between omega-3 and omega-6 fatty acids in the diet is associated with menstrual pain. Their study involved 181 healthy Danish women between the ages of 20 and 45 years who did not use oral contraceptives and who were not pregnant. The women completed 4-day food frequency questionnaires and recorded their menstrual symptoms, particularly the extent of pain. The researchers noted a strong association between increased pain and a low intake of omega-3 fatty acids from fish, between increased pain and a low intake of vitamin B12 (also present in fatty fish), and between increased pain and a low ratio of omega-3 to omega-6 fatty acids in the diet. They conclude that a higher intake of fish oils correlated with milder menstrual symptoms.
Deutch, B. Menstrual pain in Danish women correlated with low n-3 polyunsaturated fatty acid intake. European Journal of Clinical Nutrition, Vol. 49, 1995, pp. 508-16